Specimens: Whole Blood/Serum/Plasma
The CrP Rapid Test Device (Whole Blood/Serum/Plasma) is used for
semi-quantitative determination and monitoring of CrP
concentrations in whole blood/serum/plasma specimens.
C-reactive Protein (CrP) in patient’s sera has been found in
association with acute infections, necrotic conditions and a
variety of inflammatory disorders. There is a strong correlation
between serum levels of CrP and the onset of the inflammatory
process. Monitoring the levels of CrP in patient’s sera indicates
the effectiveness of treatment and the assessment of patient
recovery. It is used in particular to differentiate bacterial
infections from virus infections.
The CrP Test Strip is an immunochromatographic test, based on two
specific antibodies against human CrP. The concentration-dependent
formation of test lines allows a rapid semiquantitative
determination of CrP in whole blood samples.
The tip of the test strip is dipped into the test sample which is
diluted with buffer solution. The sample now moves through the test
strip from bottom to top. If the test sample contains CrP, it
attaches to the first anti-CrP antibody which is
conjugated with a red gold colloidal for color marking. The red CrP
antibody-gold complex, together with the sample liquid, diffuses
through the membrane that is pre dispensed with lines of different
amounts of the second anti-CrP antibody. The
CrP-antibody-gold complex is immobilized by the antibodies coated
on the membrane leading to the formation of red lines. The number
of lines depends on the CrP concentration in the sample. The more
CrP is contained in the sample, the
more red lines become visible.
The control line serves as a procedural control and indicates that
sufficient volume of specimen has been added and membrane wicking
Contact Rebecca Yan