A rapid, one step test for the qualitative detection of Cocaine Metabolite in human urine.
For healthcare professionals including professionals at point of
For in vitro diagnostic use only.
Format: Strip, Cassette, Cup,and Panel
The COC One Step Cocaine Test Strip is a rapid chromatographic immunoassay
for the qualitative detection of cocaine metabolite,
Benzoylecgonine, in human urine at a cut-off concentration of 300
This assay provides only a preliminary analytical test result. A
more specific alternate chemical method must be used in order to
obtain a confirmed analytical result. Gas chromatography/mass
spectrometry (GC/MS) is the preferred confirmatory method. Clinical
consideration and professional judgment should be applied to any
drug of abuse test result, particularly when preliminary positive
results are used.
The COC One Step Cocaine Test Strip is an immunoassay based on the principle of competitive
binding. Drugs which may be present in the urine specimen compete
against the drug conjugate for binding sites on the antibody.
During testing, a urine specimen migrates upward by capillary
action. Benzoylecgonine, if present in the urine specimen below 300
ng/mL, will not saturate the binding sites of antibody in the test
strip. The antibody coated particles will then be captured by
immobilized Benzoylecgonine conjugate and a visible colored line
will appear in the test line region. The colored line will not form
in the test line region if the Benzoylecgonine level exceeds 300
ng/mL because it will saturate all the binding sites of
A drug-positive urine specimen will not generate a colored line in
the test line region because of drug competition, while a
drug-negative urine specimen or a specimen containing a drug
concentration less than the cut-off will generate a line in the
test line region.
To serve as a procedural control, a colored line will always appear
at the control line region, indicating that proper volume of
specimen has been added and membrane wicking has occurred.
POSITIVE: One colored line appears in the control region (C). No line appears in the test region (T). This positive result
indicates that the Benzodiazepines concentration exceeds the
INVALID: Control line fails to appear. Insufficient specimen volume or incorrect procedural techniques
are the most likely reasons for control line failure. Review the
procedure and repeat the test with a new test strip. If the problem
persists, discontinue using the test kit immediately and contact
your local distributor.
1. The COC One Step Cocaine Test Strip provides only a qualitative, preliminary analytical
result. A secondary analytical method must be used to obtain a
confirmed result. Gas chromatography/mass spectrometry (GC/MS) is
the preferred confirmatory method.
2. It is possible that technical or procedural errors, as well as
other interfering substances in the urine specimen may cause
3. Adulterants, such as bleach and/or alum, in urine specimens may
produce erroneous results regardless of the analytical method used.
If adulteration is suspected, the test should be repeated with
another urine specimen.
4. A Positive Result indicates presence of the drug or its
metabolites but does not indicate level of intoxication,
administration route or concentration in urine.
Contact Rebecca Yan